spatialtis.spatial_enrichment#

spatialtis.spatial_enrichment(data, threshold=None, layer_key=None, selected_markers=None, resample=500, pval=0.01, export_key='spatial_enrichment', **kwargs)[source]#

Profiling markers spatial enrichment using permutation test

Similar to neighborhood analysis which tells you the relationship between different type of cells. This analysis tells you the spatial relationship between markers.

Parameters
dataAnnData

The AnnData to work with.

thresholdfloat

The expression level to determine whether a marker is positive

layer_keystr

The layer in AnnData to perform analysis.

selected_markerslist of str

Select your interested markers.

resampleint, default: 500

Number of times to perform resample

pvalfloat

The p-value threshold to determine significance.

export_keystr

The key used to store result.

**kwargs

Config for the analysis, for details check spatialtis.abc.AnalysisBase.